Open access
Aug 2026
Peptide language pragmatic analysis and two-stage hierarchical learning framework for therapeutic peptide prediction
TPpred-PepPA is developed, a two-stage hierarchical deep learning framework based on the ProtT5 pre-trained large language model that achieves state-of-the-art predictive performance and provides valuable interpretability for the discovery of multi-functional therapeutic peptides.
Ke Yan, Siyang Lu, Shutao Chen et al.
· BMC Biology · 0 citations