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Author

Bin Liao

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Review Open access Sep 2026

Data processing in proteomics and metabolomics: liquid chromatography–mass spectrometry-based omics with divergent computational paradigms

Abstract Proteomics and metabolomics are two foundational pillars of omics research. Proteomics focuses on the large-scale, comprehensive studies of the entire set of proteins encoded by the genome. Metabolomics targets the systematic study of chemically diverse small molecules that represent the integrated biochemical...

Amy O. Zheng, Bin Liao, Liang Zhang et al. · 0 citations
Open access Aug 2026

Proteome stability and dynamic protein complex profiling identified EEF1A1 as a novel translation regulator of autophagy and mitophagy

This work integrates thermal proteome profiling with co-aggregation analysis to monitor protein thermal stability and complex assembly dynamics in response to two canonical inducers: Torin 1, which activates autophagy via mTOR inhibition, and CCCP, a mitochondrial uncoupler that triggers mitophagy.

Shuang Zhang, Ya Zeng, Feng-Ming Li et al. · 0 citations

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