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Author

Bin Li

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Open access Sep 2026

Comparative analysis of two-dimensional and three-dimensional machine learning models for predicting the degree of invasion in lung non-mucinous adenocarcinomas presenting as subsolid nodules

Introduction Most malignant subsolid nodules (SSNs) are non-mucinous adenocarcinomas, and prognosis varies substantially with the degree of invasion. Previous studies have shown that the solid component of SSNs is closely associated with invasiveness. With advances in image analysis, three-dimensional (3D) computed tom...

Yi-Ming Hui, Ming-Zhi Lin, Bin Li et al. · 0 citations
Open access Aug 2026

Integrative transcriptomic and experimental analysis identifies GREM1 as a pro-metastatic mediator in lung adenocarcinoma

Mechanistically, GREM1 interacts with BMP2 and induces epithelial–mesenchymal transition and glycolysis via the TGF-β signaling pathway, thereby promoting LUAD progression and metastasis, and emerges as both a metastasis driver and therapeutic target.

Zhen-Qing Li, Hui-Rong Huang, Ke-Rong Zhai et al. · 0 citations

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