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Open access Sep 2026

Routine Blood Indicators Combined With Sleep Questionnaires for the Identification of Cognitive Impairment in Parkinson's Disease: A Cross‐Sectional Study With a Leakage‐Free Nested Modeling Framework

Cognitive impairment (CI) is a prevalent non‐motor complication of Parkinson's disease (PD), yet accessible and reliable screening aids remain limited. This cross‐sectional study aimed to quantify the strength of association and the cross‐sectional classification value of routine blood indicators combined with standard...

Zi-Yi Wang, TszLeong Lam, Shuo Zhang et al. · 0 citations
Review Open access Aug 2026

Immunometabolic Dysregulation in Obesity: Integrating Macrophage Polarization, Metabolic Reprogramming, and Gut Microbiota Crosstalk

Obesity is characterized by chronic low‐grade systemic inflammation, in which adipose tissue macrophages (ATMs) play a pivotal role in driving immune and metabolic dysfunction.

Yuanyuan Li, Jingwei Mao, Yiwen Deng et al. · 0 citations
Review Open access Jul 2026

Perioperative neurocognitive disorders as a neuroimmune landscape disorder: microglial priming, state heterogeneity, and time-dependent neuroinflammation

It is proposed that the brain immune landscape is a key determinant of susceptibility to PND, and time- and state-dependent, biomarker-guided intervention strategies aimed at preserving inflammatory resolution and enhancing perioperative cognitive resilience are supported.

Mengjie Chen, Jia-Qi Ning, Jia-Xi Liu et al. · 1 citation

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