Bin-Bin Tan

Integrative profiling of multi-modal plasma cfRNA signatures enables detection and prognostic risk stratification in breast cancer.

Breast cancer requires non-invasive biomarkers for accurate detection and risk stratification. We comprehensively profiled plasma cell-free RNA (cfRNA) from 41 patients with malignant and 42 with benign breast lesions using SLiPiR-seq. Multiple cfRNA subtypes displayed distinct expression patterns, and machine-learning...