Author

Biao-Qing Lu

3 papers indexed here

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Review Open access Sep 2026

Testing immune priming failure in laryngeal squamous cell carcinoma: direct evidence, unresolved links, and a compartment-resolved framework

Direct evidence for a continuous immune-priming defect in laryngeal squamous cell carcinoma (LSCC) remains incomplete. This Review therefore does not treat failed priming as an established LSCC mechanism. Instead, it separates direct LSCC observations from evidence derived from mixed-site head and neck squamous cell ca...

Wei-Zhe Hong, Guan-Jiang Huang, Qing Luo et al. · Frontiers in Immunology · 0 citations

Review Open access Aug 2026

Myeloid-derived suppressor cells in laryngeal squamous cell carcinoma: an underexplored immunosuppressive axis and strategic target for overcoming checkpoint inhibitor resistance

It is argued that combining MDSC-targeting strategies with PD-1 blockade merits dedicated clinical investigation in this disease and supported MDSCs as a clinically tractable immunosuppressive node in LSCC.

Guan-Jiang Huang, Xue-Sen Yang, Peijie Li et al. · Frontiers in Immunology · 1 citation

Review Open access Aug 2026

Cancer-associated fibroblasts and immune remodeling in laryngeal squamous cell carcinoma: evidence and translational perspectives

An evidence-stratified framework for CAF heterogeneity in LSCC is established and clarifies the translational value and current limitations of stroma-targeted strategies and provides a structured foundation for hypothesis-driven clinical and experimental investigation in laryngeal cancer.

Wei-Zhe Hong, Guan-Jiang Huang, Qing Luo et al. · Frontiers in Immunology · 1 citation