Sep 2026
Imbalance of the CaSR-SIRT3 axis exacerbates ventricular remodeling by promoting macrophage M1 polarization via the AMPK signaling pathway post-myocardial infarction.
Ventricular remodeling post-myocardial infarction (MI) is closely associated with immune responses; however, the underlying mechanisms remain incompletely understood. This study investigated whether the calcium-sensing receptor (CaSR) regulates macrophage (MΦ) polarization via the SIRT3-AMPK axis and its role in post-M...
Lin-Lin Song, Qi-Pei Liu, Nuo Chen et al.
· International Immunopharmaco... · 0 citations