Author

Bi-Hui Li

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Review Oct 2026

Izalontamab brengitecan for HR+/HER2- breast cancer in China (PANKU-Breast01): a randomised, phase 3 trial.

BACKGROUND Patients with heavily pretreated hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer have few treatment options. Izalontamab brengitecan (iza-bren) is a first-in-class, epidermal growth factor receptor and HER3 bispecific antibody-drug conjugate that cont...

B. Lan, Ye-Hui Shi, Xi-Ying Shao et al. · The Lancet · 0 citations

Review Open access Sep 2026

Enzymatic Lipid Oxygenation and Ferroptosis Resistance: A Critical Evaluation of the Lipid Antioxidant Barrier Hypothesis

This review synthesizes the emerging paradigm of directed lipid oxygenation as a regulated, adaptive mechanism that may function as a physiologically regulated lipid antioxidant barrier for ferroptosis, and examines how enzymatic lipid oxygenation generates bioactive oxylipins that activate cytoprotective transcription...

Hao Peng, Chanikarn Srinark, Chun-Xia Li et al. · Current Issues in Molecular... · 0 citations