Chemical Biology Of HER2 Signaling in HER2-Mutant Non-Small Cell Lung Cancer: Molecular Mechanisms and Therapeutic Potential of Zongertinib
Human epidermal growth factor receptor 2 (HER2/ERBB2) is emerging as an oncogenic driver. HER2 alterations include gene mutations, gene amplification, and protein overexpression in cancer cells. These alterations contribute to tumorigenesis and may differentially affect patients' responses to targeted therapies. Th...