Aug 2026
Age-Opposed Rewiring of Upstream Translation-Initiation Pattern Across Different Types of Human Cancers.
The 5' mRNA leader regulates translation through its length and upstream open reading frames (uORFs), but its systematic remodeling in cancer remains unclear. We analyzed isoform-weighted 5' leader features across The Cancer Genome Atlas, the Genotype-Tissue Expression transcriptomes and the Clinical Proteomic Tumor An...
Ayon Pal, Ranav Pal, Vivek Roy et al.
· Omics · 0 citations