Design, Development, and Characterization of Carmustine-Loaded Nanostructured Lipid Carriers for Enhanced Brain Accumulation and Antitumor Efficacy in Glioblastoma
In-vivo studies showed a reduction in tumor volume, increased accumulation of the drug in the brain, and enhanced antioxidant enzyme levels, with favorable pharmacokinetics, indicating that the nanoparticles are a promising system for the management of glioblastoma.