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Author

Betul Gundogdu

1 paper indexed here

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Sep 2026

Obesity associated elevated leptin might contribute to paclitaxel resistance via PLCB1/IP3R1 axis in head and neck cancers.

BACKGROUND Head and neck cancer (HNC) is a heterogeneous malignancy with limited therapeutic success, largely due to its complex pathogenesis and high chemoresistance. Paclitaxel is commonly used in HNC therapy; however, the frequent development of resistance reduces its efficacy. Obesity has been linked to cancer prog...

Fatma Şanli, Betul Gundogdu, O. F. Karatas · 0 citations

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