Plants produce a vast diversity of chemical compounds, yet the evolutionary history of the underlying complex metabolic networks remains poorly understood. Grasses (Poaceae family) possess a unique lignin metabolic network that can utilize both phenylalanine and tyrosine as precursors to synthesize canonical lignin as...
Bethany Moore, Yuri Takeda-Kimura, S. D. Karlen et al.· bioRxiv· 0 citations
Background: Right ventricular (RV) dysfunction in pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF) leads to adverse outcomes, yet the mechanisms underlying RV failure remain incompletely defined. We aimed to develop a multimodal framework integrating vascular mechanics and myocard...
Farhan Raza, Zachery R. Gregorich, Jack Freeman et al.· Circulation: Heart Failure· 0 citations
The grass family (Poaceae) has immense economic and ecological importance and exhibits distinctive metabolic traits, including dual starch and lignin biosynthetic pathways. We sequenced the genomes of Pharus, Joinvillea, Ecdeiocolea, and Typha species to investigate when and how these metabolic innovations evolved rela...
Yuri Takeda-Kimura, Bethany Moore, Samuel Holden et al.· Science· 0 citations
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