Author

Bertil Gummesson

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Open access Sep 2026

Rapid Translation of the Early Coding Region Promotes Premature Transcription Termination, Reducing Protein Expression in Escherichia coli.

It is proposed that excessively rapid synthesis of the N-terminal part of a polypeptide may impair its proper entry into the ribosomal exit tunnel, thereby disrupting transcription-translation coupling and exposing downstream mRNA to Rho-dependent termination.

S. Pedersen, Alberte Honoré Jepsen, Bertil Gummesson et al. · Molecular Microbiology · 0 citations