Author

Bernhard Wűnsch

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

Negative allosteric modulation of NMDA receptors with GluN2B subunit: synthesis of γ-amino alcohols embedded in a 1-benzoxepine scaffold

Novel ligands for the ifenprodil binding site of NMDA receptors with GluN2B subunit were designed, synthesized and pharmacologically evaluated. Derived from potent negative allosteric modulators, the γ-amino alcohol pharmacophore was conformationally restricted by embedding it into a 1-benzoxepine ring. Furthermore, th...

Felicitas Wendling, Yuan Chang-Halabi, Judith Schmidt et al. · RSC Medicinal Chemistry · 0 citations

Open access Jul 2026

Modulation of the agonist and antagonist activity of peptidic FPR1 ligands through N-terminal modifications: A structural and functional analysis

Formyl peptide receptor 1 (FPR1) is a promising therapeutic target for the treatment of inflammatory and infectious diseases. Although multiple classes of peptides are known to modulate FPR1 activity, comprehensive studies systematically linking N-terminal modifications to binding, mechanism of action and functional ou...

S. Maskri, Denise Pajonczyk, Joana Massa et al. · bioRxiv · 0 citations