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Bente Finsen

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Open access Sep 2026

Siponimod Induces Peripheral T Cell Redistribution Without Affecting Glial Cells or Behavior in Naïve Mice

Highlights What are the main findings? Siponimod induced pronounced peripheral T cell lymphopenia and altered lymphocyte distribution across lymphoid organs, with increased splenic T cell populations. Despite readily penetrating the blood–brain barrier, siponimod did not measurably affect glial cell densities, microgli...

Julie Damgaard Rosgaard Jakobsen, E. Thougaard, Lejla Vahl Becirovic et al. · 0 citations
Jul 2026

Proteomic and Phosphoproteomic Characterization of Disease-Associated Alterations in Nerve Terminals and Protein Inclusions of Alzheimer's Disease Patients.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by synaptic dysfunction, protein aggregation, and widespread molecular alterations in the brain. In this study, we applied quantitative mass spectrometry-based proteomics and phosphoproteomics to characterize synaptosomes and sarkosyl-in...

S. B. Elmkvist, Camilla Thygesen, Pia Jensen et al. · 0 citations

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