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Author

Benjamin T. Walters

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Open access Oct 2026

msengine: Adaptive Open-Source Signal Extraction for HDX MS

Hydrogen-deuterium exchange mass spectrometry (HDX-MS) requires extraction of broad, time-dependent peptide isotope envelopes from noise and overlapping signals. The ExMS/ExMS2 lineage established a retention-time-aware framework for raw-data extraction and integrated HDX-MS analysis. Building on this foundation, mseng...

Alexander Patapoff, Nicholas Patapoff, Benjamin T. Walters · 0 citations
#protein folding Open access Oct 2026

Peroxisome quality control is gated by a dynamic ATF6α–ABCD3 tether

The endoplasmic reticulum (ER) coordinates protein folding and lipid biosynthesis, while peroxisomes govern fatty-acid catabolism and redox balance. However, little is known about the mechanisms by which these organelles communicate. Here we show that activating transcription factor 6 (ATF6α), a cytoprotective ER-resid...

C. Noddings, Rukmini Mukherjee, Carsten Peukert et al. · 0 citations

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