Author

B. Schlechter

3 papers indexed here

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Sep 2026

Abstract A127: Targeting replication stress in pancreatic cancer: results of a phase 1b trial of azenosertib and gemcitabine in second line pancreatic cancer after progression on FOLFIRINOX

Treatment options for patients with pancreatic ductal adenocarcinoma (PDAC) who have had progressive disease on FOLFIRINOX (oxaliplatin, irinotecan, leucovorin, and infusional 5-fluorouracil) are limited, and patients are typically treated with gemcitabine and nab-paclitaxel. Targeting therapeutic vulnerabilities...

B. Huffman, Haeseong Park, Nadine A. Jackson et al. · Cancer Research · 0 citations

Sep 2026

Abstract B096: Immune and stromal features of durable complete response to radiation and dual immune checkpoint blockade in pancreatic cancer

It is suggested that productive immunotherapy responses in PDAC require not only tumor-reactive T cells, but also a stromal-vascular niche capable of supporting their recruitment, recirculation and persistence.

Sarah Kang, M. Parikh, Leontios Pappas et al. · Cancer Research · 0 citations

Open access Oct 2026

A Phase II Study of Nivolumab and Ipilimumab with Radiation Therapy in Patients with Metastatic, Microsatellite Stable Colorectal Cancer.

PURPOSE Immune checkpoint inhibitors (ICIs) have significantly altered the natural history of microsatellite instability high (MSI-H) colorectal cancer (mCRC). For microsatellite stable (MSS) refractory mCRC, ICIs recently demonstrated efficacy signals in patients without liver metastases. This study evaluated combined...

Leontios Pappas, J. Koenig, B. Yeap et al. · Clinical Cancer Research · 0 citations