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Author

Benjamin Klayman

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Review Open access Oct 2026

Suzetrigine Versus Tramadol for Acute Postoperative Pain: Systematic Review and Meta-Analysis

Opioids remain the backbone for postoperative analgesia, but adverse effects and misuse remain major concerns. Suzetrigine (VX-548), a selective NaV1.8 inhibitor, is an FDA-approved non-opioid analgesic for moderate-to-severe acute pain. This PRISMA-guided systematic review and meta-analysis evaluated the efficacy and...

Preet S. Patel, Benjamin Klayman, Raiya Patel et al. · 0 citations

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