Visible-Light-Mediated Cyclization of Intramolecular Electron Donor-Acceptor (EDA) Complexes and Its Application in the Total Synthesis of Corynanthe-Type Alkaloids.
A visible-light-driven one-pot decarboxylative cyclization cascade via an intramolecular electron donor-acceptor (EDA) complex is reported. By covalently tethering an indole donor and an NHPI ester acceptor with an alkyl linker, this strategy enables efficient assembly of the signature 6/5/6/6 tetracyclic skeleton of c...