Author

Bei-Cheng Sun

2 papers indexed here

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Open access Oct 2026

Myeloid Suppressor Cells Drive HCC Invasiveness via the THBS1-SDC4 Pathway.

BACKGROUND & AIMS Monocytic myeloid-derived suppressor cells (M-MDSCs) accumulate in hepatocellular carcinoma (HCC), but their activation and tumor-promoting mechanisms remain unclear. We investigated how stromal-myeloid-tumor crosstalk promotes HCC invasiveness and epithelial-mesenchymal transition (EMT). METHODS We...

Si-Yuan Liu, Jing-Hua Gu, Shu-Yan Sheng et al. · JHEP Reports · 0 citations

Oct 2026

Targeting the H3K4me3-HNRNPC-CD24 Axis Overcomes Stemness and Immunosuppression in Hepatocellular Carcinoma.

Hepatocellular carcinoma (HCC) is driven by cancer stemness and an immunosuppressive tumor microenvironment, which collectively contribute to therapeutic resistance. While the RNA-binding protein HNRNPC has been implicated in tumor progression, it has primarily been characterized as a downstream effector, and its auton...

D. Ye, Xue-Yin Pan, Jia-Qing Chen et al. · Cancer Letters · 0 citations