In silico analysis of missense variants in functional domains of PWWP2A and PWWP2B proteins.
Epigenetic regulatory activity through chromatin remodelling is essential for maintaining gene expression integrity, and alterations in chromatin-associated proteins can cause pathological consequences. The conserved PWWP domain in PWWP2A and PWWP2B, which are Royal family of chromatin readers, can recognize methylated...