Author

B. Lambrecht

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Open access Sep 2026

PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity

Systemic anti-tumour immunity results from T cell priming in tumour-draining lymph nodes (TDLNs)1, 2, 3–4. Although the suppression of T cells in tumours is well characterized5, 6, 7–8, whether this occurs in TDLNs—and if so, through which mechanisms—remains poorly understood. Here, using imaging mass cytometry of TDLN...

A. van Krimpen, Julie Y. Huang, Mike Eterman et al. · Nature · 0 citations

Open access Jul 2026

TNFAIP3/A20 dysfunction drives innate and sterile hyperinflammation

It is suggested that in diseases caused by insufficient TNFAIP3/A20 activity, autoantibodies may reflect a downstream consequence of disease rather than a causative driver, suggesting autoinflammatory rather than autoimmune pathology.

Karel F. A. Van Damme, Pieter Hertens, D. Sichien et al. · Frontiers in Immunology · 0 citations