Immunological and Bioinformatics Meta-Analysis Linking the TLR4-rs4986790 SNP and Bacterial Infections in Patients with Cystitis and Polynephritis
Toll-like receptor genes, especially TLR-4, produce transmembrane receptors that, depending on their expression, induce a pro- or anti-inflammatory response. TLRs are the first line of the body's defense against pathogens, including infectious ones. The most prevalent kind of mutation occurs in the human genome: single...