Open access
Jul 2026
Live single-molecule imaging reveals global shifts in mRNA mobility during human stem cell differentiation
Spatiotemporal regulation of mRNA localisation is fundamental to cell identity specification and function, yet tracking transcript dynamics in living differentiating cells remains technically challenging. Here, we establish a robust pipeline for MS2 tagging of endogenous transcripts in human induced pluripotent stem ce...
Aileen-Diane Bamford, Gilles Gut, Tim-Oliver Buchholz et al.
· bioRxiv · 0 citations