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Author

Barbara Szomolay

2 papers indexed here

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Open access Sep 2026

Exploratory single‐nucleus multiomics analysis of myeloid cell states associated with neoadjuvant chemotherapy response in pancreatic ductal adenocarcinoma

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) continues to be one of the most lethal human malignancies, with the vast majority of patients ineligible for immunotherapy. Tumour‐associated macrophages (TAMs) are key regulators of the PDAC tumour microenvironment (TME), yet their transcriptional and epigeno...

M. Ojetunde, Li Ma, Hillary G. Goodney et al. · 0 citations
Open access Jun 2026

Optimized procurement of cancer-reactive T-cell receptors from clinical samples

Abstract T-cell receptors can sense cancer-associated changes in cellular proteins, lipids, metabolites, and stress pathways, enabling immune-mediated tumour elimination in some patients. These receptors underpin T-cell receptor-based immunotherapies, yet their isolation from clinical samples remains challenging due to...

Marine E. Caillaud, C. Rius, Théo Morin et al. · 0 citations

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