Barbara H. Stokes

The single cell transcriptional signature of sexual commitment in the human malaria parasite Plasmodium falciparum

Background Malaria remains a global health challenge, with most fatal cases caused by Plasmodium falciparum in sub-Saharan Africa. A critical bottleneck in the Plasmodium life cycle is the transmission from human to mosquito, which requires a subset of blood stage parasites to switch from asexual to sexual replic...