Author

Bao-Yi Ni

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Review Open access Aug 2026

The mechano-immunological barrier in fibrosis-associated lung cancer: targeting matrix stiffness and the Piezo1 axis for microenvironment normalization

This review summarizes the Piezo1-mediated mechanotransduction networks involved in the fibrosis-to-cancer transition and discusses emerging “mechano-immunotherapeutics,” including targeted Piezo1 modulators, precision nanodelivery systems, and ECM-normalizing agents (e.g., LOX inhibitors and losartan).

Linfeng Guo, Jia Wang, Bao-Yi Ni et al. · Frontiers in Pharmacology · 1 citation · ⚡1

Review Open access Sep 2026

Cancer cachexia as an immunometabolic syndrome: targeting the immunometabolic interface with traditional Chinese Medicine monomers and formulas

This review provides a mechanistic framework for positioning TCM as a potential systemic adjuvant to break the cachexia-immunosuppression loop in modern oncology.

Bao-Yi Ni, Shu-Hang Wang, Xi Zhang et al. · Frontiers in Immunology · 0 citations