BACKGROUND
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with limited treatment options. Guchang capsule (GC) has been used in traditional Chinese medicine, but its effects on IBD and the underlying molecular mechanisms remain unclear.
METHODS
A dextran sulfate sodium (DSS)-induced colitis model...
Xiao-Hong Wang, Rong Liu, Hong Wang et al.· Molecular Immunology· 0 citations
The Review links tdLN structural, cellular, and metabolic remodeling to ICB response and resistance, highlights reinforcement of regulatory circuits after metastatic colonization, and discusses translational strategies that incorporate tdLN functional state into therapeutic design.
Cai-Yan Jia, Shu-Xuan Li, Mu-Hua Chen et al.· Frontiers in Immunology· 0 citations
This article analyses recent therapeutic trials with Bruton’s tyrosine kinase inhibitors, splenic tyrosine kinase inhibitors, and neonatal Fc receptor antagonists, demonstrating an improvement in platelet counts and patients’ quality of life.
Zhen Wang, Wu-Xia Yang, Nuo Xu et al.· Frontiers in Pharmacology· 0 citations
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