Bao Ho

Inducible expression of non-classical innate immune genes by a novel DAP-type peptidoglycan sensing and Toll signaling pathway 2266405

The Imd and Toll pathways regulate the Drosophila innate response, with each pathway activating distinct NF-κB factors and target genes. These innate immunity signaling cascades are well-studied individually, but how they intersect or cross-regulate is poorly characterized. To identify Toll and Imd interac...