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Balwina Koopal

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#protein folding Oct 2026

The bacterial antiphage protein Tiamat is an ATPase and DNase whose homologs are found across the tree of life

Bacteria and archaea encode hundreds of antiviral defense systems, some with homologs found in eukaryotic innate immunity. GHL ATPases like plant MORCs and prokaryotic Tiamat defend against viruses and phage, though their architecture and biochemical activities have remained unclear. Searching thousands of proteomes, w...

Shirley Yuan, Yuri Rafael de Oliveira Silva, Balwina Koopal et al. · 0 citations

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