Next‐generation mouse models have transformed preclinical oncology by enabling detailed study of tumor initiation, progression, immune interactions, and metastasis. Traditional systems lacked tumor heterogeneity and immune relevance. Advanced platforms such as genetically engineered mouse models (GEMMs), humanized mi...
Abhishek Sharma, Aman Kumar, Preeti Patel et al.· Advances in Therapy· 0 citations
Tuberculosis remains the leading infectious cause of death among people living with human immunodeficiency virus (HIV). An estimated 10.7 million people developed tuberculosis worldwide in 2024, including 619,000 people living with HIV, while tuberculosis caused an estimated 150,000 deaths among people living with HIV....
R. Mandal, Rahul Kumar, Balak Das Kurmi et al.· Preventive Medicine· 0 citations
An integrated omics model AI approach, supported by clinical proof and regulatory acceptance, has the potential to improve the identification of immunotherapy responders and enable more personalized treatment in TNBC.
Md Mustahidul Islam, Balak Das Kurmi, Preeti Patel· Anti-Cancer Agents in Medici...· 0 citations
Biomass/biowaste-derived polymers are an advanced approach for the preparation of biodegradable and environmentally friendly polymers from renewable sources. This review focuses on methods for preparing, characterizing, and applying polymers derived from agricultural waste, animal waste, food leftovers, forestry residu...
Lovepreet Singh, Gurpreet Singh, Balak Das Kurmi et al.· Discover Polymers· 0 citations
A nanoemulsion based gel loaded with the β-CD-MTX inclusion complex provides a hopeful approach to enhance topical MTX delivery, improves therapeutic efficacy, and reduces systemic side effects, thereby addressing important limitations of traditional RA therapy.
Aman Kumar, R. Pal, Manish Kumar et al.· BioNanoScience· 1 citation· ⚡1
Genome engineering is evolving from a DNA-cutting system to a precise and programmable genome editing system, which may support the future development of safer and more precise therapeutic strategies.
Vikash Kumar, Aman Kumar, Balak Das Kurmi· Current Pharmacogenomics and...· 0 citations
The developed transethosomal system showed favorable physicochemical properties, sustained drug release, stability, antioxidant and antimicrobial activity, and significant cytotoxicity against melanoma cells, which support its potential as a multifunctional topical platform for localized melanoma therapy and provide a...
Kirandeep Kaur, Preeti Patel, Balak Das Kurmi· Journal of Pharmaceutical In...· 0 citations
This chapter highlights the role of targeting ligands, stimuli-responsive systems, and tumor microenvironment-specific strategies in enhancing therapeutic efficacy while minimizing adverse effects, emphasizing the potential of molecularly targeted nanomedicine to advance precision therapy and improve clinical outcomes.
Aman Kumar, Md Hidul Islam, Pranav Dhingra et al.· Advances in Protein Chemistr...· 0 citations
This review highlights the structure-activity relationship (SAR) of different quinazolinone derivatives along with their binding interactions which indicate that the electronic and lipophilic characteristics of substituents on different positions of the quinazolinone core significantly affect their activity in breast c...
Simran Kaur, Shivani Kasana, Balak Das Kurmi et al.· RSC Medicinal Chemistry· 0 citations
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