Author

BaDoi N. Phan

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Open access Sep 2026

A molecular and spinal circuit basis for the functional segregation of itch and pain

Summary The dorsal horn is remarkably diverse, yet how this cellular complexity enables discrimination of sensory modalities remains a fundamental question. Neurons expressing gastrin-releasing peptide receptor (Grpr+) have long been considered dedicated to itch, yet broad activation also evokes pain-related behavior....

M. Noh, Kelly A. Corrigan, Sean-Paul G. Williams et al. · Neuron · 0 citations

Open access Aug 2026

An Epigenetic Signature of Vulnerable Neurons is Under Selective Pressure Associated with Longevity Across Placental Mammals

Age is the primary risk factor for neurodegenerative diseases, which are characterized by cell-type-specific vulnerability 1. Yet brain-aging mechanisms remain unclear given the complex, interacting age-associated pathways across diverse neural cell types. Here, we dissect cell type- cell state-specific aging gene regu...

Ghada Abdelhady, Qiao Su, Andrew Z. Wang et al. · bioRxiv · 0 citations

Open access Jul 2026

Characterization of Astrocyte Density in the Pitt–Hopkins Syndrome Mouse Model of Autism Spectrum Disorder

Germline heterozygous TCF4 LOF, which models PTHS, does not appear to significantly affect the astrocyte lineage at the cell population level, and germline heterozygous Tcf4 LOF did not result in misallocation of ventrally derived astrocytes into the dorsal cortex.

Sarain Stump, Joseph F. Bohlen, BaDoi N. Phan et al. · Neuroglia · 0 citations