Author

B. Wen

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Sep 2026

Antibiofilm efficacy of ε-polylysine hydrochloride against Enterococcus faecalis biofilms and its biocompatibility: A promising root canal medicament.

OBJECTIVES Enterococcus faecalis (E. faecalis) is a predominant pathogen associated with refractory apical periodontitis (RAP), owing to its strong biofilm-forming ability and alkali resistance, which may compromise the antimicrobial efficacy of conventional calcium hydroxide (Ca(OH)₂)-based intracanal medication. This...

Li Guo, Sheng-Long Tan, B. Wen et al. · Dental Materials · 0 citations

Review Open access Aug 2026

Endoplasmic Reticulum Stress-Driven Inflammatory Mediators in Metabolic Disorders: From Molecular Mechanisms to Targeted Therapies.

This review delineates how the canonical UPR sensors transduce metabolic stress into pro-inflammatory signaling cascades and discusses the organ-specific consequences of ERS in the liver, pancreas, adipose tissue, vascular endothelium, and hypothalamus, highlighting how this stress sustains a self-reinforcing cycle of...

B. Wen, Xiaojin Wu, Kaiying Zhang et al. · Pharmacological Research · 0 citations