Despite technological advancements over the last three decades in small-molecule omics, compound annotation remains a major bottleneck in untargeted metabolomics and non-targeted environmental analysis. This is especially true for exposomics applications, which remain significantly affected by the limited chemical spac...
V. V. Hernandes, Miguel A. Aguilar Ramos, R. Breinbauer et al.· Metabolomics· 0 citations
It is suggested that metabolic and transcriptomic immaturity constrains trained immunity in premature infants, highlighting a developmental mechanism that may affect host defense and guide future immunomodulatory strategies.
Michael Eigenschink, Elsa Davogg, Manuel Pristner et al.· MedComm· 0 citations
Humans are exposed to a multitude of non-genetic factors throughout their lives, all of which are encompassed in the concept of the exposome. To assess its chemical component, combinations of complementary analytical techniques are needed for broad chemical space coverage. However, approaches for combined organic and i...
S. Braeuer, M. L. Feuerstein, T. Buerki-Thurnherr et al.· Talanta: The International J...· 0 citations
These findings demonstrate the complementarity of SS/NTS platforms for extending chemical-space coverage for the most comprehensive exposure characterization, and efforts should be made for harmonized QA/QC provisions while conserving the added value of different workflows for exposure data for risk assessments.
Tarek Moufawad, K. Ayeni, E. Baira et al.· Environmental Science &...· 0 citations
A plate-based protein precipitation workflow in a scalable, high-throughput format for human plasma and urine demonstrates the suitability of the established protocol for combined MWAS/ExWAS.
Julia Füreder, A. Müller, Giulia Guerra et al.· Analytical Chemistry· 0 citations
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