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Open access Sep 2026

Pathological Complete Response and Safety of Neoadjuvant Pembrolizumab-Based Chemoimmunotherapy in Triple-Negative and Hormone Receptor-Low Breast Cancer: A Real-World Cohort Study

Background Neoadjuvant pembrolizumab-based chemoimmunotherapy is standard of care for early-stage triple-negative breast cancer (TNBC). Real-world data remain limited outside trial populations, particularly in the Middle East, and hormone receptor (HR)-low tumors (ER/PR 1–10%) are undercharacterised in this setting. Me...

B. Sharaf, T. Al-Batsh, Suhaib Khater et al. · 0 citations
Open access Jul 2026

Landscape of germline genetic alterations among non-western young male patients with cancer. Findings from The Jordanian exploratory cancer genetics study

Germline P/LP variants are common in young male patients with cancer, particularly at younger ages and among those meeting testing criteria, and these findings support broader implementation of germline testing to inform management and familial risk assessment.

H. Abdel-Razeq, Hira Bani Hani, Seif Alafeef et al. · 0 citations

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