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Author

B. Sahakian

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Open access Sep 2026

A wearable accelerometry landscape of human health and disease.

Digital wearable devices provide objective characterization of human behaviors in real-world settings, yet their implications for health and diseases remain incompletely understood. Here, we analyzed a large-scale accelerometry-based cohort, including 70,473 participants with up to 10 years of follow-up, yielding a tot...

Ying Liang, Yu-Jia Zhao, Yue-Ting Deng et al. · 0 citations
Open access Sep 2026

145. Cortical thinning and hippocampal expansion as brain signatures of ADHD symptom trajectories

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) affects around 5% of children and adolescents world-wide and is characterized by its significant clinical heterogeneity, including different symptom courses, such as persistent, remitting, and emergent trajectories during adolescence and adulthood, whi...

W. Hou, B. Sahakian, S. Cortese et al. · 0 citations
Open access Aug 2026

Deep learning reveals a neurocomputational mechanism predicting depression risk in adolescents

Early detection and prevention of psychiatric disorders, particularly depression, remain as major global health challenges, yet reliable tools for identifying individuals before symptom onset are lacking. Here, we combine functional neuroimaging with computational modeling to identify a mechanistic biomarker of depress...

Han Lu, Xiaoqian Yan, Benjamin Becker et al. · 0 citations

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