Review
Open access
Jul 2026
Glioblastoma as a neuro-immune network disorder: rethinking the tumor microenvironment, neural circuit integration, and therapeutic resistance
Glioblastoma, IDH-wildtype, CNS WHO grade 4, is a highly aggressive primary tumor of the central nervous system characterized by infiltrative growth, marked antigenic heterogeneity, and resistance to treatment. Despite advances in immunotherapy, clinical responses of glioblastoma remain transient and non-durable. Emerg...
Tyler Lo, Armando Bunjaj, Jeffrey P. Turnbull et al.
· Oncology Reviews · 0 citations