Author

B. Rajamani

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Open access Nov 2026

Integrated transcriptomic and proteomic profiling of RXRA-overexpressing chronic myeloid leukemia cells identifies protein kinase D as a candidate target for imatinib sensitization

Retinoid-X-receptor alpha ( RXRA ) is downregulated in chronic myeloid leukemia (CML). We previously demonstrated that overexpression of RXRA sensitizes CML cells to imatinib, but the mechanisms underlying this effect remain undefined. To characterize the molecular programs associated with RXRA-med...

Rakhi Thalayattu Vidhyadharan, R. Illangeswaran, B. Rajamani et al. · Frontiers in Pharmacology · 0 citations

Open access Oct 2026

Correction: Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo

[This corrects the article DOI: 10.3389/fphar.2023.1187066.].

B. Rajamani, R. Illangeswaran, E. Benjamin et al. · Frontiers in Pharmacology · 0 citations