Summary Diatoms are vital primary producers in marine ecosystems and play a key role in blue carbon sequestration. Although their circadian rhythms have been studied in isolation, how these rhythms are modulated by co-occurring bacteria remains unknown. Using a defined co-culture of the diatom Phaeodactylum tricornutum...
Jiwei Chen, Hang Diao, Ying-Dong Su et al.· iScience· 0 citations
Using a 1035-sample E. coli expression database, two transcriptome principles are identified that support successful TRN inference, and dominantly regulated E. coli genes are identified, suggesting that simply regulated promoter subsets are central to effective TRN inference.
Gaoyuan Li, Joshua T. Burrows, Xuwen A. Lou et al.· iScience· 0 citations
The design principles and limitations governing iModulon reconstruction and computation position the iModulon framework as an accessible, community-driven approach for reading accumulating public transcriptomes as reusable regulatory programs, enabling biological discovery and module-level design in synthetic biology.
Kangsan Kim, E. Catoiu, Yongjae Lee et al.· mSystems· 0 citations
The results demonstrate that iModulons provide a genome-scale framework for comparing transcriptional regulation across closely related organisms, revealing regulatory innovations that are not apparent from genome comparisons alone.
Heera Bajpe, Ying Hefner, R. Szubin et al.· bioRxiv· 0 citations
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