Author

B. Ogretmen

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Open access Aug 2026

Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC

The “one-two punch” approach combining LOX inhibition with clinical DHODH inhibitor suppresses tumor growth in vivo in chemo-free setting and shows that inhibiting LOX generates targetable vulnerability to ferroptosis.

O. Saatci, B. Ulukan, Metin Cetin et al. · Cell Reports Medicine · 1 citation

Open access Jul 2026

HuR—SerpinB9 Axis Regulates Tumor T-Cell Fitness and Persistence via Post-Transcriptional Control 2267776

Findings highlight a HuR-SerpinB9 axis that regulates T-cell senescence and persistence, offering a potential therapeutic target in cancer and autoimmune diseases.

P. Chakraborty, Mrinmoyee Majumder, W. Wofford et al. · Journal of Immunology · 0 citations