Review
Open access
Aug 2026
Protein O-Mannosyltransferases in Development and Disease: Evolutionary and Functional Insights from Model Organisms.
In the zebrafish model, POMT1/2 mutant phenotypes recapitulate multi-tissue defects associated with dystroglycanopathies, revealing compensatory mechanisms with broad implications for understanding these diseases and also suggesting the involvement of dystroglycan-independent pathomechanisms.
Caden Summers, S. Dauletbayeva, B. Novikov et al.
· Glycobiology · 0 citations