Author

B. Meng

2 papers indexed here

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Open access Aug 2026

Structural Basis of a High-Affinity Antibody Binding to Glycoprotein with Glycocalyx Decay

Cancer-associated defects in mucin-type O-glycosylation expose truncated glycans on cell-surface glycoproteins and create tumor-associated glycopeptide epitopes. However, the structural principles by which antibodies recognize specific MUC1 glycopeptide sequences remain incompletely defined. Here, we report the molecul...

Yun-Bin Han, Jun Niu, Deng Pan et al. · JACS Au · 0 citations

Open access Sep 2026

Structure-based design of subtype-selective psychedelic analogs

Classical psychedelics exert hallucinogenic and therapeutic effects primarily through activation of serotonin 2 A receptor (5-HT2AR), offering promise as transformative treatments for neuropsychiatric disorders. However, their concurrent activation of 5-HT2BR—associated with cardiac valvulopathy—raises serious safety c...

Hui-Qiong Li, Lingjie Tang, Jin-Feng Zhang et al. · Nature Communications · 0 citations