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Author

B. Malagutti

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Open access Sep 2026

CDKPredict: a clinicogenomic model for risk-adapted therapeutic intervention in breast cancer

Abstract Wide variation in outcomes is observed for patients with hormone-receptor-positive metastatic breast cancer (MBC) receiving first-line CDK4/6 inhibitors plus endocrine therapy (CDK4/6i+ET). Although front-line escalation strategies are beginning to enter clinical practice, assigning patients to intensified or...

Luca Boscolo Bielo, F. Sánchez-Vega, Subhiksha Nandakumar et al. · 0 citations
Review Sep 2026

Safety management of anti TROP2 ADCs in patients with breast cancer.

Safety management of TROP2-directed ADCs should be agent-specific, proactive and increasingly individualized and may incorporate pharmacogenomics, longitudinal monitoring, patient-reported outcomes and artificial intelligence to improve toxicity prediction, early detection and adaptive management.

B. Malagutti, Giulia Malvezzi, P. Zagami · 0 citations

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