Author

B. Lauzier

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Open access Aug 2026

Desmin p.R406W mutation is associated with arrhythmias through structural and electrophysiological remodeling

This study highlights the effectiveness of hiPSC-CMs and EHTs in recapitulating the clinical phenotype of desminopathy, providing a platform for investigating the mechanisms of early-onset cardiac arrhythmias and SCD.

M. Geryk, T. Stervinou, Martin Bouaud et al. · bioRxiv · 0 citations