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Author

B. Kattula

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Oct 2026

Discovery of Indazole-Based Dual-Pharmacophore Inhibitors of Dengue and Zika Proteases as Promising Antivirals

Flavivirus outbreaks caused by dengue virus (DENV) and Zika virus (ZIKV) remain a major global health challenge, with no FDA-approved antivirals available. Herein, we designed, synthesized, and evaluated indazole-based dual pharmacophore motifs targeting NS2B-NS3 serine proteases, essential for viral replication. Enz...

S. Singh, Vijayarani Potluri, Surabhi Naza et al. · 0 citations

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