Quantitative and qualitative differences in anti-Envelope IgG-secreting cells distinguish subclinical and hospitalized dengue in a Cambodian pediatric cohort.
Dengue virus (DENV) infection can result in outcomes ranging from subclinical disease to life-threatening illness, yet the antibody features mediating protection in humans remain poorly defined. Dengue virus envelope protein (E) forms homodimers on the virion surface and elicits both neutralizing and non-neutralizing a...
Amandine Trouchet, Sokchea Lay, Matteo Broketa et al.
· PLoS Pathogens · 0 citations