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B. Howden

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Open access Sep 2026

Pathogen genome enrichment sequencing to support a city-wide Legionnaires’ disease outbreak investigation

Abstract Pathogen genomics can provide high-confidence source attribution for epidemiological investigations of Legionnaires' disease (LD) outbreaks. However, the utility of culture-based genomics can be undermined by long lead times for Legionella pneumophila culture or a lack of isolates when dealing with non-cultura...

K. Mercoulia, J. Lacey, G. Taiaroa et al. · 0 citations
Open access Aug 2026

Genomic epidemiology and emerging antimicrobial resistance profiles of Salmonella Paratyphi A in returning travellers to Australia

Enteric fever is endemic to many low- and middle-income countries (LMICs), particularly those in sub-Saharan Africa, South and South-East Asia. The causative agents are typhoidal serovars of Salmonella enterica, including Typhi (S. Typhi) and Paratyphi A (SPA). There are no vaccines currently licensed for SPA, leaving...

C. Connor, R. Wick, M. Taouk et al. · 0 citations
Open access Aug 2026

Loss of GdpP function in Staphylococcus aureus confers β-lactam-specific antibiotic tolerance and promotes invasive infection

It is demonstrated that an enhanced level of cyclic-di-AMP (CDA), which results from GdpP loss-of-function mutations, promotes tolerance specifically to the β-lactam class of antibiotics in Staphylococcus aureus.

V.D. Hayatnagarkar, S. Giulieri, Raymond Poon et al. · 0 citations

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