Author

B. Hildebrandt

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Open access Sep 2026

CRISPR/Cpf1-mediated editing of DNM1L in induced pluripotent stem cells.

The dynamin-1-like protein (DNM1L), also termed DRP1, is essential for mitochondrial fission. Mutations in DNM1L are associated with neurological disorders and cardiac dysfunction. To decipher the role of DNM1L in human induced pluripotent stem cells (hiPSCs) and in their differentiated counterparts, we used CRISPR/Cpf...

Roohallah Ghodrat, H. Ramachandran, B. Hildebrandt et al. · Stem Cell Research · 0 citations