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Author

B. Fiske

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2 papers indexed here

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Review Open access Oct 2026

Considerations for therapeutic targets for clinical trials in biomarker-characterized prodromal Parkinson's disease populations

Parkinson's disease (PD) is a growing public health problem and biologically targeted therapeutics (BTTs) that slow disease progression are urgently needed. However, the development of effective BTTs is challenging as PD is a clinically defined syndrome with pathobiological heterogeneity and the pathobiological process...

R. Schneider, G. Skibinski, B. Fiske et al. · 0 citations
Open access Sep 2026

α-Synuclein Seeding Discriminates Between LRRK2 G2019S Variant Carriers with and Without Parkinson's Disease.

BACKGROUND Reliable biomarkers for Parkinson's disease (PD) pathology detection are essential for research. α-Synuclein (aSyn) seed amplification assay (SAA) is a validated biomarker for misfolded aSyn. OBJECTIVE The aim was to assess the association between aSyn SAA and LRRK2-related PD (LRRK2-PD) and its link to mi...

Theresa Lüth, C. Gabbert, T. Kleinz et al. · 0 citations

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